Whilst it is the first to flower, Nebbiolo is the last to ripen, which means it is susceptible not only to spring frosts but also early autumn frosts. It requires good drainage and will sulk in the rain, meaning the growing regions it does best in have all their rainfall in the winter and have mostly dry spring, summer and autumn seasons. The one viticultural godsend of this fickle variety is in its thick skins, which are very disease resistant later in the season.
Found historically in Barolo and Barbaresco, with new world plantings in Australia and Okanagan Valley showing the diversity of style this variety can produce.